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Explore the Science

JOINT HEALTH - ROSEHIP, TURMERIC & VETPERINE

OVERVIEW

VetActiv8 Joint Health is a potent, natural anti-inflammatory, designed to reduce pain and swelling to keep your dog active, happier and healthier for longer. 


The formula is a blend of 3 powerful ingredients that synergise together to assist in reducing inflammation, that may combat pain and swelling in joints.

Rosehip

Rosehip is a natural anti-inflammatory which can help reduce pain, stiffness, swelling and assists to boost the immune system.

VetActiv8 Joint Health’s rosehip has standardised daily dose levels of vitamin C -113mg per scoop. Studies show that consuming more vitamin C increases your blood antioxidant levels by up to 30%. Antioxidants inhibit the migration of white blood cells to joints with tissue damage, resulting in a reduction of inflammation in these areas. In addition, vitamin C is a co-factor in collagen synthesis, the main protein in joint tissue and bone. Vitamin C is also well known to assist the immune system.

Rosehip is used to treat and aid many health conditions such as assisting with; poor skin, hair and coat, boost immunity and eye and bone health. The reason for its wide use is that it contains vitamin C, A, E, and B-complex, as well as calcium, iron, selenium, manganese, magnesium, phosphorous, potassium, sulfur, silicon, and zinc. Furthermore, it contains compounds, such as lycopene, pectin, lutein, beta-carotene which are very powerful and essential to the body. 


Curcumin

VetActiv8 Joint Health uses a patented active that has a minimum of 95% curcuminoids, the active that reduces inflammation and assists with joint health. The three types of curcuminoids used in the formula are curcumin, demethoxycurcumin (DMC) and bisdemothoxycurcumin. These curcuminoids are responsible for blocking key inflammatory pathways and have shown to lower the number of chondrocyte cells destroyed, which are an integral part of cartilage.  VetActiv8 Joint Health’s turmeric is highly potent in deactivating pain sensitivity mechanisms in the body thus decreasing swelling and protecting joint tissue from damage.


VetPerine

VetActiv8 Joint Health’s formula synergises these ingredients with VetPerine, which is a natural extract that enhances the oral bioavailability of raw materials. VetPerine is clinically proven to increase the bioavailability of curcumin by 2000%, and the uptake of Vitamin C by 52.7%.  This active, further enhances our key active ingredients to effectively reduce inflammation, pain and swelling caused by arthritis and other joint problems. 

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The Results

CLINICAL EVIDENCE

Vitamin C Protects Chondrocytes against Monosodium Iodoacetate-Induced Osteoarthritis by Multiple Pathways

Mol. Sci. 2017, 18, 38; doi:10.3390/ijms18010038

 

Vitamin C possessed multiple capacities for prevention of OA progress.

Influence of Piperine on the Pharmacokinetics of Curcumin in Animals and Humans

Planta Med. 1998; 64(4):353-6

 

VetPerine enhances the oral bioavailability of curcumin in both animals and humans.

Therapeutic Roles of Curcumin: Lessons learned from Clinical Trials

The AAPS Journal, Vol. 15, No. 1, January 2013 (# 2012)

Curcumin has shown therapeutic potential against a number of diseases, including Arthritis

Rosehip - An Evidence based herbal medicine

 

Australian Family Physician Vol. 41, No. 7, july 2012

 

Treatment with standardised rosehip powder consistently reduced pain scores.

Does the hip powder of Rosa canina (rosehip) reduce pain in osteoarthritis patients?

 

Osteoarthritis and Cartilage (2008) 16, 965e972

 

Treatment with standardised rosehip powder consistently reduced pain scores.

Curcumin-attenuated trinitrobenzene sulphonic acid induces chronic colitis by inhibiting expression of cyclooxygenase-2.

World J Gastroenterol 2006 June 28; 12(24): 3848-3853

Curcumin has therapeutic effects on TNBS acid-induced colitis, the mechanisms seem to be related to COX-2 inhibition and PGE2 improvement.

Dietary Methyl Donor Depletion Protects Against Intestinal Tumorigenesis in ApcMin/+ Mice

J Interferon Cytokine Res 2011;31:219-26

Curcuminoids reduced expression inflammatory mediators such as CCL2, 1L-1β, 1L-6, and TNF-α, in the intestinal tissue of a mouse tumour model 

Anti-Inflammatory Effects of Resveratrol, Curcumin and Simvastatin in Acute Small Intestinal Inflammation

PLoS One 2010;5:e15099

Curcuminoids ameliorated acute inflammation of theP ileum by; increasing the level of anti-inflammatory cytokine IL-10, downregulating Th1-type immune responses

WHAT DO PEOPLE SAY

TESTIMONIALS

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CODY, 12 YEARS OLD, NSW

Cody was getting stiff joints and over time he needed to get injections for his arthritis as it got to a point where he would hop on 3 legs as he couldn't walk on one of them. We thought we would give VetActiv8 Joint Health a try as we wanted a more natural approach if there was one available.
 
He has been on it for about 2 months, and we have seen such an improvement as he now enjoys his walks and no longer struggled going up steps.

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