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Explore the Science

Synbiotic Boost – Pre/Probiotics & Digestive Enzymes


VetActiv8 Synbotic Boost is a premium prebiotic and probiotic formula, innovatively tailored for the canine digestive and immune system. Studies have shown that the digestive system are directly related to optimum health, wellbeing, and overall performance. If the digestive system is imbalanced, clinical signs of illness/disease, behavioural disorders, decreased performance and reduction in general health and wellbeing may result. 

VetActiv8 Synbiotic Boost contains unique multi-strain probiotics. The formula includes at least 50Bn CFUs. This high count will ensure that enough bacteria will make it through the digestive track to where they are needed. VetActiv8 Synbiotic Boost includes Saccharomyces boulardii the probiotic most commonly associated with reduction of diarrhoea. These probiotics work synergistically to maintain a heathy balance of intestine and gut flora. 

Prebiotics are important for digestive health as they act like food for probiotics. The blend of prebiotics has been specifically chosen to stimulate growth and activity of the formula’s probiotic, ensuring a more effective product. 

Colostrum is rich in immuno - globulins (antibodies) known to stimulate the immune system. Studies show that adult dogs can greatly benefit from the daily intake of colostrum, with improved immune responses and gut function.  

Digestive Enzymes

Digestive Enzymes are essential to this formula because they assist in breaking down food, and aid the digestive system to absorb the required nutrients.

The Results


Probiotics in prevention of antibiotic associated diarrhoea: meta-analysis


10.1136/bmj.324.7350.1361 on 8 June 2002

The meta-analysis suggests that probiotics can be used to prevent antibiotic associated diarrhoea and that S boulardii and lactobacilli have the potential to be used in this situation. 

Supplementation of diets with bovine colostrum influences immune function in dogs

British Journal of Nutrition (2013), 110, 2216–2221

Diets supplemented with Bovine Colostrum significantly influence immune response in dogs.


Nancy Loes, DVM MBA

The beneficial (“good”) bacteria contribute directly to the maintenance or restoration of health through multiple mechanisms, including the stimulation of the immune system, the processing of nutrients, and the production of vitamins and fatty acids that support normal intestinal function.

Understanding the canine intestinal microbiota and its modification by pro-, pre- and synbiotics – what is the evidence?

DOI: 10.1002/vms3.17 (2016)

This review summarises the current knowledge of the intestinal microbiome composition in the dog and evaluates the evidence for probiotic use in canine GI diseases to date.

Efficacy Of Saccharomyces Boulardii As A Probiotic In Dogs With Lincomycin Induced Diarrhoea

Bull Vet Inst Pulawy 51, 365-369, 2007

S. boulardii was effective in treating lincomycin induced diarrhoea and to prevent the occurrence of diarrhoea when given together with lincomycin.

Bovine colostrum: A veterinary nutraceutical


Journal of Veterinary Medicine and Animal Health Vol. 3(3), pp. 31-35, July 2011


Bovine colostrum can be given alone as a treatment to reduce the length and severity of established infections or it can be used in conjunction with traditional treatments such as antibiotics

Effect of Saccharomyces boulardii in dogs with chronic enteropathies: double-blinded, placebocontrolled study

Veterinary Record: first published as 10.1136/vr.104241 on 6 December 2017

In dogs with Chronic Enteropathies, the results of the current study suggest that S boulardii is effective in improving the control of clinical signs, compared with standard therapy, without short-term adverse effects. All dogs included in the study showed improvements in GI signs, but some significant differences between dogs receiving S boulardii and controls were observed.

Effects of probiotic Lactobacillus acidophilus strain DSM13241 in healthy adult dogs

AJVR, Vol 65, No. 3, March 2004

Probiotic was able to survive passage through the canine intestinal tract, leading to enrichment of the colonic microflora and local and systemic effects. 

Oral Administration of β-1,3/1,6-Glucan to Dogs Temporally Changes Total and Antigen-Specific IgA and IgM

Clinical and Vaccine Immunology, Feb. 2010, p. 281–285

This study is the first to evaluate the adjuvant effect of orally administered β-1,3/1,6-glucans in healthy dogs on the total IgM, IgA, and IgG concentrations in serum; the IgA concentrations in tears and saliva; and the isotype-specific antibody response against Bordetella. There seems to be a temporary decrease in the switch from IgM toward IgA due to oral MacroGard supplementation in dogs, so that serum and mucosal IgA levels decrease. The same effect on a systemically induced serum antibody response against a Bordetella vaccine was seen.

Oat beta-glucan as a dietary supplement for dogs

PLOS ONE | July 31, 2018

It is concluded that oat beta-glucan extract can be used as a dietary supplement for dogs at a dose of 10 g/kg of food, being effective in reducing blood concentrations of total cholesterol, LDL-c and VLDL-c as well as CTTAD of nutrients. These results demonstrate the potential of using this type of beta-glucan in the diet of obese animals. In addition, by reducing the predominance of a Th2 response, oat beta-glucan can positively modulate the vaccine response of animals.



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Cody was getting stiff joints and over time he needed to get injections for his arthritis as it got to a point where he would hop on 3 legs as he couldn't walk on one of them. We thought we would give VetActiv8 Joint Health a try as we wanted a more natural approach if there was one available.
He has been on it for about 2 months, and we have seen such an improvement as he now enjoys his walks and no longer struggled going up steps.

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